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Carlos Aquino, a 63 year old Filipino male with hormone-refractory prostate cancer is your clinic patient. Aquino was diagnosed with benign prostatic hypertrophy (BPH) several years ago and was taking alpha blockers for this condition.A year ago, his BPH symptoms worsened despite maximal therapy.
Petrylak said that it does make sense to add another agent to ADT in high-volume disease, given that there are theoretically more genetic abnormalities, more mutations, and a higher chance of drug resistance.A few years ago he immigrated to the US ( sponsored by his sister who is in the US).He has been married to his wife for 35 years and has three adult children . Aquino complained of escalating back, flank, rib, and leg pain. Later that month, a bone scan demonstrated increased uptake throughout skull, ribs, and thoracic and lumbar spine, as well as a slightly increased uptake in the proximal L femur. The patient was seen by uro-oncology and treated with two courses of mitoxantrone and prednisone.In addition to radiotherapy Vic received an androgen deprivation (AD) drug called Lucrin in a clinical trial known as RADAR (Randomised Androgen Deprivation and Radiotherapy).By inhibiting testosterone levels it shrinks the prostate and thus also shrinks the prostate cancer tissue.He reports moderate pain control on his current pain regimen.He also states that his appetite is poor and that he tires easily.Prostate cancer remains the second leading cause of death in men in the United States as of 2012.It is estimated that prostate cancer affected more than 241,000 new men in 2012, with 15% of these patients presenting with advanced disease.In order to increase knowledge about how best to respond to and alleviate the suffering of seriously ill patients, we have created a free training module on Physician Assisted Death. As medicine becomes more complex and specialized by the minute, the communication gulf between doctors and their patients is becoming progressively insurmountable.A unique opportunity to view lively discussions featuring peer-to-peer exchanges that provide authoritative insights, opinions, and perspectives on important issues facing today's cancer care professionals.