Research Paper On Genetics

Research Paper On Genetics-89
The genetic structures of the SCA cohorts from Brazil and US differ considerably on the genome-wide, chromosome 11 and Hb S mutation locus levels.Individuals carrying an FMR1 expansion between 55 and 200 CGG repeats, are at risk of developing the Fragile X-associated tremor/ataxia syndrome (FXTAS), a late onset neurodegenerative disorder characterized by cerebellar gait ataxia,...more Background: Hypertension is considered as a major cause of morbidity and mortality throughout the world and become a major global burden on public health in many developing countries. Apart from environmental factors, multiple genes have been responsible for hypertension.

The genetic structures of the SCA cohorts from Brazil and US differ considerably on the genome-wide, chromosome 11 and Hb S mutation locus levels.Individuals carrying an FMR1 expansion between 55 and 200 CGG repeats, are at risk of developing the Fragile X-associated tremor/ataxia syndrome (FXTAS), a late onset neurodegenerative disorder characterized by cerebellar gait ataxia,...more Background: Hypertension is considered as a major cause of morbidity and mortality throughout the world and become a major global burden on public health in many developing countries. Apart from environmental factors, multiple genes have been responsible for hypertension.

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Recently, in our high-resolution study, we were able to quantify the admixture dynamics of these groups, which has suggested a male-biased admixture.

Here, we added the newly available ancient samples and revisited the interplay of genes and cultures.

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The point mutation responsible for sickle cell anaemia codes for a variant hemoglobin, sickle hemoglobin or Hbs, whose presence drives the pathophysiology of disease.

Here we propose to explore ancestry and population structure in a genome-wide study with particular emphasis on chromosome 11 in two SCA admixed cohorts obtained from urban populations of Brazil (pernambuco and são paulo) and the United states (pennsylvania).

The point mutation responsible for sickle cell anaemia codes for a...

more Genetic analysis of admixed populations raises special concerns with regard to study design and data processing, particularly to avoid population stratification biases.

In this study, we focussed on the migration of Jewish and Parsi populations on temporal and spatial scales.

The existence of Jewish and Parsi communities in India are recorded since ancient times.

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